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SINGLE-CHAIN ANTIBODIES
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DeCS
Descriptor
English
:
Single-Chain Antibodies
Descriptor
Spanish
:
Anticuerpos de Cadena Única
Descriptor
Portuguese
:
Anticorpos de Cadeia Única
Tree Number:
D12.644.541.500.650.500.800
D12.776.124.486.485.114.224.785
D12.776.124.486.485.680.650.500.800
D12.776.124.790.651.680.650.500.800
D12.776.377.715.548.680.650.500.795
Definition
English
:
A form of
antibodies
consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.
See Related
English
:
Single-Domain Antibodies
History Note
English
:
2010
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53639
Unique Identifier:
D057127
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS